34 research outputs found

    Novel Betaherpesvirus in Bats

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    Because bats are associated with emerging zoonoses, identification and characterization of novel viruses from bats is needed. Using a modified rapid determination system for viral RNA/DNA sequences, we identified a novel bat betaherpesvirus 2 not detected by herpesvirus consensus PCR. This modified system is useful for detecting unknown viruses

    Successful Surgical Resection following Bronchial Artery Embolization in a Case of Lung Cancer Complicated with Massive Hemoptysis

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    Hemoptysis is sometimes observed in lung cancer patients and can be life-threatening. We present a case with severe hemoptysis that was resolved by bronchial artery embolization (BAE) followed by surgery. The presence of necrotic tissue in the majority of the resected tumor and only few cancer cells was presumed to be from loss of bronchial artery blood flow. Although BAE is not a standard therapy for lung cancer, it can be useful and may be considered by physicians as one of the treatment options prior to surgical resection in cases with hemoptysis

    Association of objectively measured daily physical activity and health utility to disease severity in chronic heart failure patients: A cross-sectional study

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    Background and aims Physical activity (PA) levels are related to mortality and morbidity in patients with chronic heart failure (CHF). Health utility (HU), a very important cost-effectiveness analysis for health care and health status, is measured by several preference-based utility measures. This study aimed to evaluate the relation between PA and HU and the effect of disease severity on PA and HU in patients with CHF. Methods We enrolled 226 consecutive outpatients with CHF (mean age, 57.5years; males, 79.6%) in this retrospective cross-sectional study. Patients were divided into three groups by NYHA class for classification of disease severity. Patient characteristics, average step count in steps/day, PA energy expenditure (PAEE) in kcal/day for 7days as assessed by accelerometer, and HU assessed by Short Form-6D were compared between the groups. Results Average step count (r=0.37, P<0.01) and average PAEE (r=0.36, P<0.01) correlated positively with HU in all patients. Patients were classified into three groups by NYHA class: class I (n=92), class II (n=97), and class III (n=37). Average step counts (7618.58, 6452.51, and 4225.63 steps/day, P<0.001), average PAEE (244.65, 176.88, and 103.72kcal/day, P<0.001), and HU (0.68, 0.63, and 0.57, P<0.001) respectively decreased with the increase in NYHA class (P<0.001). Conclusion This study showed a significant relationship of daily PA and HU to disease severity in patients with CHF. Although causation cannot be determined from this study, these results suggest that PA and HU may provide important information related to the severity of disease in patients with CHF
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